Advantra-Z™ - Additional Information, Clinical Trials & Research Data

Advantra-Z™

This page contains additional details information, clinical trials and research data pertaining to the patented ingredient Advantra-Z™, as well as its related chemical forms. You may print this page for your records if you wish.

Below you'll find numerous research studies, clinical data and proven scientific information on how and why Advantra-Z works, as well its safety. Man of the compilations utilize the patented and original forms of Advantra-Z, but some are also with its generic forms such as "bitter orange" and "citrus aurantium".

	Efficacy Studies
2005	Increase in the Thermic Effect of Food in Woman by Citrus aurantium, Gougeon et al, McGill Nutrition and Food Science Center, published in OBESITY RESEARCH
	Abstract: The Effects of Acute Citrus aurantium Ingestion on Energy Expenditure in Mildly Obese Subjects, Seifert
	Effect of Multi-Ingredient Weight-Loss Product (LeanSource) Containing Citrus aurantium on Body Composition in Overweight Adult Men & Women, Zenk
2003	The Difference Between Citrus aurantium Extract (Advantra Z^®) and Ephedra Extract, Jones
2002	Citrus aurantium as a Thermogenic, Weight-reduction Replacement for Ephedra: An Overview, Preuss/DeFerndinando, published in the JOURNAL OF MEDICINE
1999	Effects of Citrus aurantium (Advantra ZŽ), Caffeine and St. John's Wort on Body Fat Loss, Lipid Levels, and Mood States in Overweight Healthy Adults, Colker, published in Current Therapeutic Research
	Thermic Effect of Citrus aurantium on Obese Subjects, Pathak/Gougeon, McGill Nutrition and Food Science Center
	Thermogenic Effect of Beta-Sympathicomimetic Compounds Extracted from Citrus aurantium, in Humans, Hedrei/Gougeon, McGill Nutrition and Food Science Center
	Mechansim Of Action
2002	Advantra ZŽ: Observation on its Effects and Mechanism of Action, Jones
	Safety/Toxicity Studies
2005	Absence of QTc-Interval Prolonging or Hemodynamic Effects of a Single Dose of Bitter-Orange Extract in Healthy Subjects, Min, et. al., University of Connecticut, published in Pharmacotherapy
	Hemodynamic Effects of Ephedra-Free Weight-Loss Supplements in Humans, Haller, University of California, San Francisco, published in the AMERICAN JOURNAL OF MEDICINE
	Synephrine Pharmacokinetics and Cardiovascular Changes After Ingestion of Citrus aurantium Dietary Supplements (abstract), Haller, University of California, San Francisco, presented at the Annual Conference of the American Society of Clinical Pharmacology and Therapeutics
2004	Pharmokenetics and Drug Disposition; in Vivo Assessment of Botanical Supplementation on Human Cytochrome P450 Phenotypes: Citrus aurantium, Echinacea Purpurea, Milk Thistle and Saw Palmetto, Gurley, published in American Society of Clinical Pharmacology and Therapeutics
2001	Seville (sour) Orange Juice: Synephrine Content and Cardiovascular Effects in Normotensive Adults, Penzak/Jann
1997	An Acute Oral Toxicity Study in Rats With Advantra ZŽ, Douds